Response to Letter by van Dijk et al

Response to letter of Vahle et al.

several important points that deserve comment. The primary objective of our paper was to report the results of a standard two-year rat carcinogenicity study conducted with recombinant full-length human PTH (1-84) to comply with international regulatory guidelines. Dr. Vahle et al. are correct that our study did not directly compare the carcinogenic potential of PTH (1-84) and PTH (1-34), that i...

Response letter regarding the letter to the editors by Brown et al.

We read with interest the letter by Brown and colleagues, which focuses on our model’s assumptions regarding duration of cross-protection against non-vaccine HPV types (20, 30, 50 y and lifetime). Brown et al. begin by highlighting an article reviewing cross protection in different vaccine trials by Malag on et al., which suggests that AS04-adjuvanted HPV16/18 (bHPV, CervarixTM) vaccine-mediate...

Letter to the Editor response: Nygaard et al.

The article by Nygaard and others (2016) proposes that applying batch correction approaches to microarray data from studies with unbalanced designs may inadvertently exaggerate the differences observed. In seeking to illustrate their point, Nygaard and others (2016) utilized a dataset (GSE61901) from a study we published (Towfic and others, 2014) and showed that one analysis pipeline utilizing ...

Hylke van Dijk Democratic processing

Response to Comment on: van Dijk et al. Exercise Therapy in Type 2 Diabetes: Is Daily Exercise Required to Optimize Glycemic Control? Diabetes Care 2012;35:948–954

We thank Thosar and Wallace (1) for their interest and constructive comment related to our recent work published inDiabetes Care (2). As this was the first study that investigated the impact of the frequency of exercise (within a fixed volume) on glycemic control, we specifically designed a short-term intervention study during which glycemic control was assessed over 48 h with exercise and diet...